He was born on May 7, 1975. He graduated from Kazakh State Architecture & Construction Academy (Almaty) as an architect-designer and L.N. Gumilyov Eurasian National University (Astana) with a major in economy and management. He is a Candidate of Economic Sciences.
In different years Zhenis Kassymbek worked as head of Railway Transport & Ports Division in Agency for Regulation of Natural Monopolies & Competition Protection, head of Tariff Policy Division in Coordination & Tariff Policy Department, director of Water-Borne Transport Department in Ministry of Transport and Communications, director of Aktau International Sea Port Republican State Enterprise.
From 2005 he was vice minister of transport and communications.
From 2009 he was executive secretary of Ministry of Transport and Communications.
From March 2014 he was minister of transport and communications, Republic of Kazakhstan.
Since August 2014 he worked as first vice minister of investments and development, Republic of Kazakhstan.
From June 2016 he was minister for investments and development, Republic of Kazakhstan. (reassigned – 13.09.2016–26.02.2018).
From December 2018 to February 2019 he was minister of industry and infrastructure development.
On Feb. 25, 2019, he was appointed the Deputy Prime Minister by the Decree of the President.